VISDB Viral Integration Site DataBase

VIS ID

TVIS10007438

Fusion event

HBV-DIXDC1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

299

Orient

-

Integrated sequence

TACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTG| |TCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATC

Chromosome

chr11

Cytoband

q23.1

Reference genome

Start

End

111879121/112008397 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-615-3p ; hsa-mir-16-5p ; hsa-mir-582-3p ; hsa-mir-582-5p

Nearest miRNA

hsa-mir-10392/Upstream/494882; hsa-let-7a-2/Downstream/1441626;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/30721, chr11-CpG: 77/Downstream/16455

Upstream sequence

accaagattcataaaccaagtccttagagacctacaaagagacttagactcccacacaataataatgggagacttttacaccccactgtcaatattagat

Downstream sequence

caacgagacagattaacaaggatatccatgacttgaactcagctctgcaccaagcagacctaatagacatctacagaactctccaccccaaatcaacaga