Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007439
Fusion event
HBV-HSD17B6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
1009
Orient
-
Integrated sequence
TGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCT| |TTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACT
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
Start
End
57171099/56777315 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/2440001; hsa-let-7i/Downstream/417189;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/24766, chr12-CpG: 79/Downstream/228769
Upstream sequence
cactagagtagctgggactacaggggtgcaccaccatgcctggctaatttttgtattttttgtagacatgaggtttctccatgttgcccatgttggtctc
Downstream sequence
agactcctgggctcaagccaaccacttgccttggccttccaaagtgTAAAtttttttttttttttggaaatggagttttgctcttgttgccccggctggc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.