Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007453
Fusion event
HBV-MYH13 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1795
Orient
-
Integrated sequence
CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
Start
End
10252503/10349186 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1253/Upstream/2162182; hsa-mir-10226/Downstream/1732713;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/150063, chr17-CpG: 25/Downstream/288978
Upstream sequence
TCTCTCTCtttctctttctttctttctctttatttcatggagtttcacgattttcacccaggctgaagtgcagtggtacaatcttggctcactgcaacct
Downstream sequence
ccacctcccgggatcaagtgattctcctgcctcagtctcccgagtagctgggaatacaggcaggcaccattatgcccagctaatttgtatttttagtaga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.