VISDB Viral Integration Site DataBase

VIS ID

TVIS10007460

Fusion event

HBV-PLA2G4C integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1051

Orient

-

Integrated sequence

GAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGC| |GTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCC

Chromosome

chr19

Cytoband

q13.33

Reference genome

Start

End

48583918/48080661 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-132-3p ; hsa-mir-124-3p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-10395/Upstream/853640; hsa-let-7e/Downstream/929245;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/18594, chr19-CpG: 24/Downstream/56800

Upstream sequence

actttgggaggctgaggaggggagatcactcgaggtcaggcgttcaagaccagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaatt

Downstream sequence

agctggatgcggtggtgcacatctgtagtcccagctacttgggaggctgaggcaggagaatcacttgaacccacgagttggaggttgcagtgagattgca