Basic Information
VIS ID
TVIS10007467
Fusion event
HBV-chr21 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1443
Orient
-
Integrated sequence
GTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGC| |TGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGC
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
End
10781804/10730651 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10396a/Upstream/1742986; hsa-let-7c/Downstream/2675733;
Nearby gene
TEKT4P2(-813211) ; TPTE(+124939) ;
Upstream sequence
gaatgaggtggaaacgaatggaatttaagggagtgtagtggagtggagttgagaggaatgctatggaatggaatggaatggagtggagtggagaggattg
Downstream sequence
gagtggactggagtggaatggagtggagtggagtagagaggagtggagtggaatgacatgaaatagaatggagggcagtggaaaggatttgaaaggagtg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate