VISDB Viral Integration Site DataBase

VIS ID

TVIS10007481

Fusion event

HBV-PDE10A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1789

Orient

-

Integrated sequence

GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG

Chromosome

chr6

Cytoband

q27

Reference genome

Start

End

166244656/165831168 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1287-3p ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-7151-5p ; hsa-mir-5681b ; hsa-mir-5579-5p ; hsa-mir-33a-3p

Nearest miRNA

hsa-mir-10398/Upstream/7066415; hsa-mir-1913/Downstream/678186;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/3780, chr6-CpG: 29/Downstream/22853

Nearby gene

PDE10A(-169068) ; LINC00473(+92880) ;

Upstream sequence

GGTGTGCACGTGGAGGTAGGGAAGGTGTGTGCAGGGGAATTGTATATACTCACACTATATCAATATCTGGACATATCTCACACTGGATCTGGAAAGCCAC

Downstream sequence

ggtcaagagatcgagaccatggtgaaaccccgtctctactaaaaatacaagaaactagcctggcgtggtggtaggcgcctgcagtcccagctacttggga