Basic Information
VIS ID
TVIS10007491
Fusion event
HBV-chrY integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1226
Orient
-
Integrated sequence
TAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGC| |CATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTA
Host Sequence
Chromosome
chrY
Cytoband
q12
Reference genome
GRCh37/hg19
Start
28784360/26638213 (Hg38)
End
28784360/26638213 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/13158947;
Nearest TSS
ENST00000430575/Upstream/909723;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/10816, chrY-CpG: 36/Downstream/30429432
Nearby gene
TTTY3B(-904825) ;
Upstream sequence
tggtagtttcttttgctgtgcagaaggtctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatgaa
Downstream sequence
gaatggaaaggagtggagtggaatggaatggagtggagtggaatgtagtggaatggaatggaatggattggaatggaatggagtggagtggaatggagtg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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