VISDB Viral Integration Site DataBase

VIS ID

TVIS10007508

Fusion event

HBV-TOR1AIP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

476

Orient

-

Integrated sequence

GGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTG| |TCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACC

Chromosome

chr1

Cytoband

q25.2

Reference genome

Start

End

179821843/179852708 (Hg38)

Orient

+

Location type

UTR5

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-21-5p ; hsa-mir-455-3p ; hsa-mir-125a-5p ; hsa-mir-138-2-3p ; hsa-mir-3611 ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-98-3p ; hsa-mir-1284 ; hsa-mir-7977 ; hsa-mir-1273e ; hsa-mir-4266 ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-144-3p ; hsa-mir-302f ; hsa-mir-2467-3p ; hsa-mir-4649-3p ; hsa-mir-6125 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-4520-2-3p ; hsa-mir-498 ; hsa-mir-4520-3p ; hsa-mir-142-3p ; hsa-mir-124-5p ; hsa-mir-4255 ; hsa-mir-4668-5p ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-7515 ; hsa-mir-4307 ; hsa-mir-5584-5p ; hsa-mir-942-3p ; hsa-mir-4802-3p ; hsa-mir-33a-3p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-4536-5p ; hsa-mir-3650 ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-648 ; hsa-mir-5586-3p ; hsa-mir-510-3p ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-203a-3p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-3065-3p ; hsa-mir-6813-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-6885-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4684-5p ; hsa-mir-6831-3p ; hsa-mir-627-3p ; hsa-mir-6513-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-3926 ; hsa-mir-383-3p ; hsa-mir-548s ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-6771-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-605-3p ; hsa-mir-6511a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/48683; hsa-mir-1182/Downstream/585606;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/107892, chr1-CpG: 23/Downstream/25036

Upstream sequence

AGTGCCAGACAAATCAGTCTTACCCTCTTGAGGTTCCCTAAGTCCACTGTCGGCCATGTTTGTGTTCTATCTCTTCAGAGTTGGGAGGATACTTTTTTTA

Downstream sequence

GTACTTGGTTTTCCTTGTGAAGATGTCTTGTTTTCTTCTTGTCCCAAGTCCCAACAGACTCATGCTTCCCATGGACCCAGGAAATAAGGCATATATACAG