VISDB Viral Integration Site DataBase

VIS ID

TVIS10007509

Fusion event

HBV-TOR1AIP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

222

Orient

-

Integrated sequence

AATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTG| |ACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCC

Chromosome

chr1

Cytoband

q25.2

Reference genome

Start

End

179822409/179853274 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-21-5p ; hsa-mir-455-3p ; hsa-mir-125a-5p ; hsa-mir-138-2-3p ; hsa-mir-3611 ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-98-3p ; hsa-mir-1284 ; hsa-mir-7977 ; hsa-mir-1273e ; hsa-mir-4266 ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-144-3p ; hsa-mir-302f ; hsa-mir-2467-3p ; hsa-mir-4649-3p ; hsa-mir-6125 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-4520-2-3p ; hsa-mir-498 ; hsa-mir-4520-3p ; hsa-mir-142-3p ; hsa-mir-124-5p ; hsa-mir-4255 ; hsa-mir-4668-5p ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-7515 ; hsa-mir-4307 ; hsa-mir-5584-5p ; hsa-mir-942-3p ; hsa-mir-4802-3p ; hsa-mir-33a-3p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-4536-5p ; hsa-mir-3650 ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-648 ; hsa-mir-5586-3p ; hsa-mir-510-3p ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-203a-3p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-3065-3p ; hsa-mir-6813-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-6885-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4684-5p ; hsa-mir-6831-3p ; hsa-mir-627-3p ; hsa-mir-6513-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-3926 ; hsa-mir-383-3p ; hsa-mir-548s ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-6771-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-605-3p ; hsa-mir-6511a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/49249; hsa-mir-1182/Downstream/585040;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/108458, chr1-CpG: 23/Downstream/24470

Upstream sequence

TCTTCAATTTCTGTCCCAGATAATTTTCTCATAGTCTGCCTATCAGGAGCTTTCACTTATATTAAAAAGTAACAATGCACAGGAGGTTCCCACAAACTGA

Downstream sequence

GATGGCTGCTTTGAGGTGTACCACTACACATTTGGACTGACTTTGAAGTGGTTTTCTCGAAGTATTCTTTTGTAAAATATGGAGACAGATATTCCTTTAT