VISDB Viral Integration Site DataBase

VIS ID

TVIS10007511

Fusion event

HBV-XPR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1958

Orient

+

Integrated sequence

CTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTT| |GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT

Chromosome

chr1

Cytoband

q25.3

Reference genome

Start

End

180669415/180700279 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-7-5p ; hsa-mir-320b ; hsa-mir-455-3p ; hsa-mir-382-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-205-5p ; hsa-mir-92b-3p ; hsa-mir-493-3p ; hsa-mir-155-5p ; hsa-mir-5189-3p ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-6818-3p ; hsa-mir-4713-5p ; hsa-mir-1251-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-6814-5p ; hsa-mir-6796-3p

Nearest miRNA

hsa-mir-101-1/Upstream/261889; hsa-mir-1182/Downstream/12016049;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/67599, chr1-CpG: 128/Downstream/211901

Upstream sequence

atggtagtttcttttgctgtgcagaagctcttgagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatga

Downstream sequence

agtccttgcccacgcctatgtcctgaatggtaatgcctaggttttcttctagggtttttatggttttaggtctaacgtttaaatctttaatccatcttga