Basic Information
VIS ID
TVIS10007512
Fusion event
HBV-LINC01036 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
1958
Orient
+
Integrated sequence
CTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTT| |GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
187313962/187344830 (Hg38)
End
187313962/187344830 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
LINC01036
Nearest miRNA
hsa-mir-101-1/Upstream/6906440; hsa-mir-1182/Downstream/5371498;
Nearest TSS
ENST00000473358/Upstream/37436; ENST00000614505/Downstream/296396;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/663881, chr1-CpG: 56/Downstream/5463672
Nearby gene
PLA2G4A(-355849) ;
Upstream sequence
atggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatga
Downstream sequence
agtccttgcccacgcctatgtcctgaatggtaatgcctaggttttcttctagggtttttatggttttaggtctaacgtttaaatctttaatccatcttga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate