Basic Information
VIS ID
TVIS10007515
Fusion event
HBV-LOC105372922 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2018
Orient
+
Integrated sequence
ATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCG| |GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
218183631/218010289 (Hg38)
End
218183631/218010289 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105372922
Nearest miRNA
hsa-mir-101-1/Upstream/5932604; hsa-mir-1182/Downstream/2107564;
Nearest TSS
ENST00000473358/Upstream/117389; ENST00000420347/Downstream/21546;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/379154, chr1-CpG: 120/Downstream/154149
Nearby gene
LINC00210(-89485) ; RRP15(+274998) ;
Upstream sequence
tggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatgaa
Downstream sequence
gtccttgcccacgcctatgtcctgaatggtaatgcctaggttttcttctagggtttttatggttttaggtctaacgtttaaatctttaatccatcttgaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate