GRIP1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007551
Fusion event
HBV-GRIP1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2055
Orient
+
Integrated sequence
TTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCAC| |CATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAG
Host Sequence
Chromosome
chr12
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
66976914/66583134 (Hg38)
End
66976914/66583134 (Hg38)
Orient
+
Location type
Intronic
Target gene
GRIP1
Nearest miRNA
hsa-let-7i/Upstream/331977; hsa-mir-1178/Downstream/2690023;
Nearest TSS
ENST00000382841/Upstream/12076; ENST00000539109/Downstream/64215;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/347510, chr12-CpG: 105/Downstream/485756
Upstream sequence
catggtactggtaccaaaacagagatatagatcaatggaacagaacagagccctcagaaataacgccgcatatctacaaccatctgatctttgacaaacc
Downstream sequence
tgagaaaaacaagcaatggcgaaaggattccctatttaataaatggtgctgggaaaactggctagccatatgtagaaagctgaaactggatcccttcctt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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