VISDB Viral Integration Site DataBase

VIS ID

TVIS10007558

Fusion event

HBV-SORD integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2081

Orient

+

Integrated sequence

TACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCT| |TTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATG

Chromosome

chr15

Cytoband

q21.1

Reference genome

Start

End

45347040/45054842 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-484 ; hsa-mir-10a-5p ; hsa-mir-6836-3p ; hsa-mir-378a-5p ; hsa-mir-6749-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-345-5p ; hsa-mir-3653-5p ; hsa-mir-4469 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6514-3p ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3945 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-3622b-5p ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-6873-3p ; hsa-mir-9-3p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-942-5p ; hsa-mir-302a-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-483-3p

Nearest miRNA

hsa-mir-10393/Upstream/336949; hsa-mir-11181/Downstream/378208;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/31497, chr15-CpG: 101/Downstream/56208

Upstream sequence

tgcctaggttttcttctagggtttttatggttttaggtctaacgtttaagtctttaatccatcttgaattgatttttgtataaggtgtaaggaagggatc

Downstream sequence

cagtttcagctttctacatatggctagccagttttcccagcaccatttattaaatagggaatcctttccccattgtttgtttttctcaggtttgtcaaag