VISDB Viral Integration Site DataBase

VIS ID

TVIS10007562

Fusion event

HBV-PHKB integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1958

Orient

+

Integrated sequence

CTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTT| |GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT

Chromosome

chr16

Cytoband

q12.1

Reference genome

Start

End

47679188/47645277 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-484 ; hsa-mir-6882-3p ; hsa-mir-4312 ; hsa-mir-100-3p ; hsa-mir-4258 ; hsa-mir-1265

Nearest miRNA

hsa-mir-1225/Upstream/13481604; hsa-mir-11401/Downstream/2647339;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/183981, chr16-CpG: 31/Downstream/599144

Upstream sequence

atggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatga

Downstream sequence

agtccttgcccacgcctatgtcctgaatggtaatgcctaggttttcttctagggtttttatggttttaggtctaacgtttaaatctttaatccatcttga