VISDB Viral Integration Site DataBase

VIS ID

TVIS10007571

Fusion event

HBV-PRPSAP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2326

Orient

-

Integrated sequence

ACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAA| |CACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAG

Chromosome

chr17

Cytoband

q25.1

Reference genome

Start

End

74306238/76310157 (Hg38)

Orient

-

Location type

downstream

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-16-5p ; hsa-mir-615-3p ; hsa-mir-3152-5p ; hsa-mir-4674 ; hsa-mir-6836-3p ; hsa-mir-502-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4437 ; hsa-mir-378g ; hsa-mir-1915-5p ; hsa-mir-6841-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-5193

Nearest miRNA

hsa-mir-10226/Upstream/212081; hsa-mir-1250/Downstream/426293;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/1810, chr17-CpG: 128/Downstream/42913

Upstream sequence

tcactgcaatctctgcctcttgggttcaaccaattaattctcctgcctcagcctcccgagtagctgggattacaggcgtgcaccccctcccccaacaccc

Downstream sequence

ggctaatttttgtatttttagtagggacagggtttcaccatattggccaggctggtctcaaactcctgacctcaagtgatctgcccacctcggcctccca