CCDC102B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007574
Fusion event
HBV-CCDC102B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2018
Orient
+
Integrated sequence
ATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCG| |GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
66526637/68859400 (Hg38)
End
66526637/68859400 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC102B
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1-2/Upstream/1777714; hsa-mir-548av/Downstream/3993921;
Nearest TSS
ENST00000575820/Upstream/13005; ENST00000579651/Downstream/42855;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/144062, chr18-CpG: 174/Downstream/540873
Upstream sequence
caagatggattaaagatttaaacgttagacctaaaaccataaaaaccctagaagaaaacctaggcattaccattcaggacataggcgtgggcaaggactt
Downstream sequence
catgtccaaaacaccaaaagcaatggcaacaaaagccaaaattgacaaatgggatctaattaaactaaagagcttctgcacagcaaaagaaactaccatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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