VISDB Viral Integration Site DataBase

VIS ID

TVIS10007588

Fusion event

HBV-MGAT5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1958

Orient

+

Integrated sequence

CTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTT| |GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT

Chromosome

chr2

Cytoband

q21.2

Reference genome

Start

End

134967825/134210254 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-502-3p ; hsa-mir-769-5p ; hsa-mir-181a-5p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-7847-3p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-5189-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-3680-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-7850-5p ; hsa-mir-4529-3p ; hsa-mir-4520-2-3p ; hsa-mir-8058 ; hsa-mir-5009-5p ; hsa-mir-1269b ; hsa-mir-1269a ; hsa-mir-3121-5p ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-5581-3p ; hsa-mir-1236-3p ; hsa-mir-6845-3p ; hsa-mir-3667-3p ; hsa-mir-877-3p ; hsa-mir-5685 ; hsa-mir-6872-3p ; hsa-mir-4690-3p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-6768-5p ; hsa-mir-5681a ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-6738-3p ; hsa-mir-5001-3p ; hsa-mir-6886-3p ; hsa-mir-938 ; hsa-mir-6505-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-3941 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-629-3p ; hsa-mir-29b-2-5p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6742-5p ; hsa-mir-92a-2-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-193b-5p ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4695-5p ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-4438 ; hsa-mir-484

Nearest miRNA

hsa-mir-1285-2/Upstream/83062; hsa-mir-10b/Downstream/647566;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/18098, chr2-CpG: 147/Downstream/507874

Nearby gene

MIR3679(-83062) ; MGAT5(+44005) ;

Upstream sequence

atggtagtttcttttgcggtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatga

Downstream sequence

agtccttgcccacgcctatgtcctgaatggtaatgcctaggttttcttctagggtttttatggttttaggtctaacgtttaaatctttaatccatcttga