Basic Information
VIS ID
TVIS10007598
Fusion event
HBV-LOC107985840 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2067
Orient
+
Integrated sequence
CTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTC| |AGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATG
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
3184873/3181102 (Hg38)
End
3184873/3181102 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107985840
Nearest miRNA
hsa-mir-10b/Downstream/2793560;
Nearest TSS
ENST00000437798/Upstream/24346; ENST00000482645/Downstream/13289;
Nearest CpG islands
chr2-CpG: 83/Target, None/Upstream, None/Downstream
Nearby gene
MYT1L(-849828) ; EIPR1(+7868) ;
Upstream sequence
ACATGGGGACGCTCACTATTCCAGCACCGACACGGGGTCGCTCACTATTCCAGCACCGACACGGGGACACTCACTATTCCAGCACCGACACGGGGCACCG
Downstream sequence
ACACGGGGACGCTCACTATTCCAGCACCGACACGGGGACGCTCACTATTCCAGCACCGACACGGGGCACCGACACGGGGACGCTCACTGTTCCAGCACCG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate