VISDB Viral Integration Site DataBase

VIS ID

TVIS10007606

Fusion event

HBV-SLC24A3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1958

Orient

+

Integrated sequence

CTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTT| |GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT

Chromosome

chr20

Cytoband

p11.23

Reference genome

Start

End

19401688/19421044 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7c-3p ; hsa-mir-3177-5p ; hsa-mir-4475 ; hsa-mir-4668-5p ; hsa-mir-511-3p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548t-3p ; hsa-mir-5584-5p ; hsa-mir-624-3p ; hsa-mir-7845-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/950353; hsa-mir-1-1/Downstream/6787142;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/207786, chr20-CpG: 127/Downstream/336351

Upstream sequence

aggattccctatttaataaatggtgctgggaaaactggctagccatatgtagaaagctgaaactggatcccttccttacaccttatacaaaaatcaattc

Downstream sequence

aagatggattaaagatttaaacgttagacctaaaaccataaaaaccctagaagaaaacctaggcattaccattcaggacataggcgtgggcaaggacttc