Basic Information
VIS ID
TVIS10007631
Fusion event
HBV-LINC02502 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2018
Orient
+
Integrated sequence
ATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCG| |GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG
Host Sequence
Chromosome
chr4
Cytoband
q27
Reference genome
GRCh37/hg19
Start
120870948/119949793 (Hg38)
End
120870948/119949793 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02502
Nearest miRNA
hsa-mir-12113/Upstream/5292939; hsa-mir-1305/Downstream/5557466;
Nearest TSS
ENST00000502981/Upstream/10253; ENST00000503073/Downstream/90822;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/320698, chr4-CpG: 54/Downstream/116669
Nearby gene
PDE5A(-320967) ; MAD2L1(+109631) ;
Upstream sequence
atttcacactgaggaaactagtgattaggcaggctgggtaaattatctaagatctgaaatgatcaagtagaatttgaattcacatcttcctaacttcaaa
Downstream sequence
gtccttgcccacgcctatgtcctgaatggtaatgcctaggttttcttctagggtttttatggttttaggtctaacgtttaaatctttaatccatcttgaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate