Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007641
Fusion event
HBV-TEC integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2326
Orient
-
Integrated sequence
ACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAA| |CACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAG
Host Sequence
Chromosome
chr4
Cytoband
p12
Reference genome
Start
End
48172926/48170909 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/518166; hsa-mir-1243/Downstream/4541773;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/153487, chr4-CpG: 49/Downstream/98436
Nearest cancer related gene
TEC(OG, No orient, 0)
Upstream sequence
atatctacccaaagggaaataagtcattacatcaaaaagacacctacatgcatctgtttattgcagcacaatttcaaagatatggaaccaatctaagtac
Downstream sequence
gcatggtggtgggtgcctgtaatcctagctacttaggaggctgaggcaggagaatcgcttgaacccaggaggcggagattgcagtgagccgagatcacac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.