VISDB Viral Integration Site DataBase

VIS ID

TVIS10007646

Fusion event

HBV-GRID2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1959

Orient

+

Integrated sequence

TACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTG| |CCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATA

Chromosome

chr4

Cytoband

q22.2

Reference genome

Start

End

94530449/93609298 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-448

Nearest miRNA

hsa-mir-12113/Upstream/6308715; hsa-mir-1243/Downstream/5388089;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/1303442, chr4-CpG: 112/Downstream/219046

Upstream sequence

AAAAACACAATTTAAAATGATTTGAGACAATTCTTCAGCCTAAATTCCAAGTTTGTCTTTAGATGTAACTGCAACACAATCCCCAAAATTAATTAGTCAT

Downstream sequence

agaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttgggcatgaagtccttgcccacgcctatgtc