VISDB Viral Integration Site DataBase

VIS ID

TVIS10007658

Fusion event

HBV-NPR3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2326

Orient

-

Integrated sequence

ACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAA| |CACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAG

Chromosome

chr5

Cytoband

p13.3

Reference genome

Start

End

32736195/32736089 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-30a-5p ; hsa-mir-335-5p ; hsa-mir-98-5p

Nearest miRNA

hsa-mir-10397/Upstream/341614; hsa-mir-103a-1/Downstream/3411803;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/21745, chr5-CpG: 55/Downstream/704440

Upstream sequence

GAGGGAAGTGGTGGTGGAAAAACAGATGGTTTTCTTGTTGGGAAATAAACTTTAAGGAGAGAAGAATATGTCCTTTGAGTTTATTCATAAGTCCACAAAG

Downstream sequence

gtgtggtggcgcatgtctgtaaccccagctactcgggaggctgaggcgggagaattgcttgaaccctggaggcaaaggttgcagtgagctgagatcatgc