Fusion event
HBV-ATG10 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|Polymerase|
Integrated sequence
ACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAA| |CACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAG
End
81322736/82026917 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/9148254; hsa-mir-103a-1/Downstream/813238;
Upstream sequence
agagtcaattatgccatgcttttctaaatgaacagaaatattattaagtaaccttacatatcacacttcttgattgtttctatcccactgagcgactatc
Downstream sequence
gcatggtggtgggtacctgtaattccagctactcgagaggctgaggcaggagaatcgcttgaacccaggaggcggagtttgcagtgagccgagatcacac
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.