Basic Information
VIS ID
TVIS10007672
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1958
Orient
+
Integrated sequence
CTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTT| |GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
End
16861170/16860939 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/719315; hsa-mir-10398/Downstream/1710845;
Nearby gene
ATXN1(-99449) ;
Upstream sequence
CTTATTACATAATGTACCAATGGGGAAAATATTCATTTCAACAGTACGTGGCCAATGTTTTTCACCATAAAATTCTGTCAGAGAAACAAGAAGTCCCTGA
Downstream sequence
aagatggattaaagatttaaacgttagacctaaaaccataaaaaccctagaagaaaacctaggcattaccattcaggacataggcgtgggcaaggacttc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate