VISDB Viral Integration Site DataBase

VIS ID

TVIS10007674

Fusion event

HBV-PKHD1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1958

Orient

+

Integrated sequence

CTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTT| |GCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCAT

Chromosome

chr6

Cytoband

p12.2

Reference genome

Start

End

51744413/51879615 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-759 ; hsa-mir-892c-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-4727-3p ; hsa-mir-6826-5p ; hsa-mir-1296-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-552-5p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-4323 ; hsa-mir-4482-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-9-3p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-6504-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-4700-3p ; hsa-mir-892c-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-891b ; hsa-mir-574-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p

Nearest miRNA

hsa-mir-10398/Upstream/6681845; hsa-mir-10524/Downstream/264734;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/1028897, chr6-CpG: 54/Downstream/404736

Upstream sequence

TACAAAAGCTCAAATTCTAAAAAATTTAGAAGTTCTGCTTTTAAAAGAATAATCTAAAGCAATTGAAATTATACTTCAGTGACCACAGCAATCTCTTTTA

Downstream sequence

aagatggattaaagatttaaacgttagacctaaaaccataaaaaccctagaagaaaacctaggcattaccattcaggacataggcgtgggcaaggacttc