ZFAND2A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007678
Fusion event
HBV-ZFAND2A integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2326
Orient
-
Integrated sequence
ACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAA| |CACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAG
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
1189649/1150013 (Hg38)
End
1189649/1150013 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
ZFAND2A
Nearest miRNA
hsa-mir-339/Upstream/126987; hsa-mir-10399/Downstream/694167;
Nearest TSS
ENST00000635602/Upstream/11753; ENST00000413706/Downstream/5664;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/11394, chr7-CpG: 113/Downstream/9316
Nearby gene
C7orf50(-11756) ; ZFAND2A(+2894) ;
Upstream sequence
cctagaacgtaagctacatacagcatagacGGAGGATAGGGTCCAATAACAACTGGTCAATGGTTACCCAATAAATATTTGCTGAGCAAACATCTGGATG
Downstream sequence
ggctaatttttgtatttttagtagggacagggtttcatcatgttggccaggctggtctcaaactcctCCaaataccacaatgtaccccatcaatatgtac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate