Fusion event
HBV-ENPP2 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|Polymerase|
Integrated sequence
ACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAA| |CACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAG
End
120612105/119599865 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12123/Upstream/274600; hsa-mir-10400/Downstream/3615923;
Upstream sequence
GTTCTGTTGACATAACTGTTGAATCACTTCCCCCCACTCACTTGTTCAAGGAGGCAAGGTTTTGTTTCCTGGGGGTAATATCTAAGCCATTCACAGCCTG
Downstream sequence
gcatggtggtgcacgcctgtaatcccagctactcgggaggctgagacaggagaatcacttgaacctgggaggtggaggttgcagtgagccaagatcacac
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.