VISDB Viral Integration Site DataBase

VIS ID

TVIS10007700

Fusion event

HBV-BNC2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2018

Orient

+

Integrated sequence

ATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCG| |GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG

Chromosome

chr9

Cytoband

p22.3

Reference genome

Start

End

16466778/16466780 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-629-3p ; hsa-mir-3973 ; hsa-mir-6510-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-8064 ; hsa-mir-892a ; hsa-mir-297 ; hsa-mir-4666b ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-455-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-873-3p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4499 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-2278 ; hsa-mir-561-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-17-3p ; hsa-mir-545-5p ; hsa-mir-410-3p ; hsa-mir-6867-3p ; hsa-mir-516a-5p ; hsa-mir-4713-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6740-3p ; hsa-mir-942-5p ; hsa-mir-1264 ; hsa-mir-510-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4315 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-3691-3p ; hsa-mir-3908 ; hsa-mir-568

Nearest miRNA

hsa-mir-101-2/Upstream/10458876; hsa-let-7a-1/Downstream/2106526;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/913444, chr9-CpG: 30/Downstream/260081

Upstream sequence

ctttttcacccctacaAAACCCATAACATGTTAGCTCAGTCAGAGCCTTCCCCCTCAAAAAGTAACATGCTAATTTCTTTTAATTGGGTTCAGTTATGTT

Downstream sequence

catgtccaaaacaccaaaagcaatggcaacaaaagccaaaattgacaaatgggatctaattaaactaaagagcttctgcacagcaaaagaaactaccatc