VISDB Viral Integration Site DataBase

VIS ID

TVIS10007702

Fusion event

HBV-UBAP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2125

Orient

+

Integrated sequence

TTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTA| |ATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCT

Chromosome

chr9

Cytoband

p13.3

Reference genome

Start

End

33966632/33966634 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-122-5p ; hsa-mir-34a-5p ; hsa-mir-320a ; hsa-let-7f-5p ; hsa-let-7a-5p ; hsa-mir-218-5p ; hsa-mir-335-3p ; hsa-mir-6801-5p

Nearest miRNA

hsa-mir-101-2/Upstream/498699; hsa-let-7a-1/Downstream/1641460;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/148332, chr9-CpG: 75/Downstream/82007

Upstream sequence

TAATGGAAATGTTAAAATTCATATCTGATTAACATTTTTAATAACTTAGAGGAGATTTTAACTTTATTTAAAAATAGGTAAAATTATTGTACCTAATTAT

Downstream sequence

aacatgttgcataatattaacatacaaatcttgcatatacgtagtcagaaataactatttcttgtttttttggtactactaaaaaaagtactgtttttct