VISDB Viral Integration Site DataBase

VIS ID

TVIS10007724

Fusion event

HBV-CHM integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

150

Orient

-

Integrated sequence

GTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCG| |CTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTC

Chromosome

chrX

Cytoband

q21.2

Reference genome

Start

End

85204886/85949881 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p

Nearest miRNA

hsa-let-7f-2/Upstream/46174; hsa-mir-105-1/Downstream/9113260;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/705003, chrX-CpG: 66/Downstream/198058

Upstream sequence

TAAGTCAATTCTTTTTTTATCAAGATTATAATGCTGGTCACATCCAACATGAGTTTATATGCTTAGGAAGGGTGGTTGAGGGAGATTTTCTTCCTCAGCC

Downstream sequence

GGAAGGGGAATGTCCATGGGAAACACTGATCCCCATGTACATACAATACAAACCCTAACCTGAAATAAAAGCTTTGAGCAATAAACACTGAAATTAAata