Basic Information
VIS ID
TVIS10007738
Fusion event
HBV-LOC105371413 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|Polymerase|
Start
1615
Orient
-
Integrated sequence
CGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAG| |ACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAG
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89322169/89255761 (Hg38)
End
89322169/89255761 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371413
Nearest miRNA
hsa-mir-11401/Upstream/539424;
Nearest TSS
ENST00000527434/Upstream/27069; ENST00000602042/Downstream/12343;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/7574, chr16-CpG: 48/Downstream/1111
Nearby gene
ZNF778(-26204) ; ANKRD11(+11860) ;
Upstream sequence
gtcagccccagtctgctgagtctgtctcctgatctggggcagcggtttgccctgtggcctttcctctctcacagacctaagaaggaccgtcgatattttc
Downstream sequence
cagcctgtttagccttttacttgttgggatagaatatggccagttccaaacttcctacctgctggaGACCTGGGGtccacacgtttccttaacaccatca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate