VISDB Viral Integration Site DataBase

VIS ID

TVIS10007740

Fusion event

HBV-MED24 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1726

Orient

+

Integrated sequence

CGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTT| |AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT

Chromosome

chr17

Cytoband

q21.1

Reference genome

Start

End

38178454/40022201 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-24-3p ; hsa-mir-766-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-197-3p ; hsa-mir-16-5p ; hsa-mir-3680-3p ; hsa-mir-3941 ; hsa-mir-216b-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-8067 ; hsa-mir-6508-5p

Nearest miRNA

hsa-mir-1180/Upstream/295640; hsa-mir-10226/Downstream/4131;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/40964, chr17-CpG: 19/Downstream/32313

Upstream sequence

TCCAGCTGTCAGGGAAAAGAGCTTGAGCTCCGATTTGAGCGAGGTCAGCATGGCTAGCAGGGCCTCAGCCCCTCTCTGCTCAACCCCTCCCACAATCTGA

Downstream sequence

CAGGCCCCTTGTGCCCATGGGCAAGCTGGGGCCACACAAATCACCCATGCAGATTCCTGACCAATCATGCCCAGGCACAGCTGCCCCAAGGGCAGGGGCC