Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007751
Fusion event
HBV-FAM157B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1592
Orient
-
Integrated sequence
CCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCT| |TCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGAC
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
End
141152919/138262469 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7a-1/Upstream/423953;
Nearest TSS
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/41329, None/Downstream
Nearby gene
FAM157B(-18747) ;
Upstream sequence
tatgtgctaaatgctacatacatttgtaaactctccctatatattacaagatggtttgcttcaaaagcttttttctcaccaacttattcccacaagcagt
Downstream sequence
agtacaaaagagagaaattttaaagctggatgtccaggggagacatcacacgtcggcaggttccgtgatgccccccaagccgcaaaaccaacaagttttt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.