VISDB Viral Integration Site DataBase

VIS ID

TVIS10007756

Fusion event

HBV-NCOR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2426

Orient

-

Integrated sequence

CACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAG| |ATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCA

Chromosome

chr17

Cytoband

p12

Reference genome

Start

End

15943095/16039781 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1301-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-34a-3p

Nearest miRNA

hsa-mir-1253/Upstream/788085; hsa-mir-10226/Downstream/242233;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/39407, chr17-CpG: 118/Downstream/175180

Upstream sequence

TTATTTCTGAAAGGCCAATCAGGAAACAAACATGCATTGCCCCATCAGCCCACTGAATACACACAGCACTTGGCAAGTGACCTAGAACAATACCAGGACC

Downstream sequence

CACCACACAGAGACCtttttttttggagacagagtctctctctgtcgcacccaggctggagtgcagtggcgcgatcttggctcactgcaacctccgcctc