VISDB Viral Integration Site DataBase

VIS ID

TVIS10007757

Fusion event

HBV-NCOR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1823

Orient

+

Integrated sequence

TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA

Chromosome

chr17

Cytoband

p12

Reference genome

Start

End

15943285/16039971 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1301-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-34a-3p

Nearest miRNA

hsa-mir-1253/Upstream/788275; hsa-mir-10226/Downstream/242043;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/39597, chr17-CpG: 118/Downstream/174990

Upstream sequence

cctccgcctcccagattcaagggattctcctacctcagtctcccaagtagctgggactacaggcacccaccaccacaccaggctaattttttgtattttt

Downstream sequence

aggagatggggtttcaccatattggtcaggctgatctcgaattccgaacctcaggtgatccgcccgccttggcctcccaaagtgctgggattacaggcgt