Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007771
Fusion event
HBV-ZNF804B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1734
Orient
-
Integrated sequence
AAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTG| |GGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCT
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
Start
End
88632979/89003665 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/13088396; hsa-mir-10399/Downstream/3200350;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/243696, chr7-CpG: 98/Downstream/1114913
Upstream sequence
AACTCTCAAACTCCCCAATAATTGCACATGCATGGCCTCAGACATCCAAGGGGCTCCCGTTGTCATGAACACCATTTTGACCGGATACATTGTCTTCGCT
Downstream sequence
gccagaatcagaatgaaatcaaaatgttcagattcaaagccaagtgctcttctgagtgcctcgtgctgcctcTTACATTAGACTACTTCTGACCCACAGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.