VISDB Viral Integration Site DataBase

VIS ID

TVIS10007855

Fusion event

HBV-MYO3B integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1765

Orient

-

Integrated sequence

TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT

Chromosome

chr2

Cytoband

q31.1

Reference genome

Start

End

171274896/170418386 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1-3p

Nearest miRNA

hsa-mir-128-1/Upstream/1835368; hsa-mir-10b/Downstream/4749247;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/590267, chr2-CpG: 44/Downstream/293426

Upstream sequence

ATTTCTGAGTCTGACAATAAAGCATTGTTGGTTTGTCTTCTACATAACTAAGCTGAGTTAAAATGCATCTTTTTATTAGCAGAGGCATTATTGTATTAAT

Downstream sequence

ATCATCGCTACTAAATTTTCTCTTTGCAAAACTAGAATTTTAAGCTGGAATCTGGAGAAGTGTGATTTCCCTGGAAAAGAGTTTGTAGACCTCTTTGTTT