MYO3B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007870
Fusion event
HBV-MYO3B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1799
Orient
-
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
End
171274898/170418388 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-128-1/Upstream/1835370; hsa-mir-10b/Downstream/4749245;
Upstream sequence
TTCTGAGTCTGACAATAAAGCATTGTTGGTTTGTCTTCTACATAACTAAGCTGAGTTAAAATGCATCTTTTTATTAGCAGAGGCATTATTGTATTAATAT
Downstream sequence
CATCGCTACTAAATTTTCTCTTTGCAAAACTAGAATTTTAAGCTGGAATCTGGAGAAGTGTGATTTCCCTGGAAAAGAGTTTGTAGACCTCTTTGTTTGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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