Fusion event
HBV-COP1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
TCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTC| |TTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGAC
End
176116444/176147308 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/178829; hsa-mir-1182/Downstream/882055;
Nearest cancer related gene
Upstream sequence
ACACGCAAATAGACTTACATGGAAGAAGAAAATATAACCACTCACTTCAATCTGTCTGCACTAAAACATATTTTCTAGACTAAAGCTTATTATAATTACA
Downstream sequence
AATCACTATAGTACCCAATTCCAATTATTGTGAAATTCAAGAAATTTAATCAAAGTAGTAGATAAACGTTTACAATTTGTTACCTAGCTCCTCAGAATTT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.