VISDB Viral Integration Site DataBase

VIS ID

TVIS10007895

Fusion event

HBV-SFPQ integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1836

Orient

+

Integrated sequence

AGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGC| |CTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTA

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

35646365/35180764 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-141-3p ; hsa-mir-29b-3p ; hsa-mir-1229-3p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-331-3p ; hsa-mir-10a-5p ; hsa-mir-218-5p ; hsa-mir-498 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-1296-5p ; hsa-mir-6508-3p ; hsa-mir-5697 ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p ; hsa-mir-5694 ; hsa-mir-383-5p

Nearest miRNA

hsa-mir-12136/Upstream/511070; hsa-mir-101-1/Downstream/1980799;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/59774, chr1-CpG: 98/Downstream/11102

Nearby gene

ZMYM1(-64910) ; SFPQ(+2836) ;

Nearest cancer related gene

SFPQ(OG, No orient, 0)

Upstream sequence

CTCAACTTGTAGAATTACCAAGATTGCATAATGAAATTACTGATATTGCCGATCTATGGGCAGGTCAGTTTGCTACAATAGAGACTAATTATCACATGCT

Downstream sequence

ATACGGTCCATGTCAAGGTGCTAAAAGCACCCTAGTTCCCAAGTATAGTTTAGTTCCCTCTCCCCCACACCACTGATGTGTTCCATGTTATCTTCAGTTA