Basic Information
VIS ID
TVIS10007904
Fusion event
HBV-LOC105376387 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1805
Orient
-
Integrated sequence
TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
6913579/6871617 (Hg38)
End
6913579/6871617 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105376387
Nearest miRNA
hsa-mir-3155a/Upstream/719340; hsa-mir-107/Downstream/5259143;
Nearest TSS
ENST00000439456/Upstream/92019; ENST00000420049/Downstream/48855;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/290937, chr10-CpG: 30/Downstream/300263
Nearby gene
LINC00707(-28711) ; SFMBT2(+287007) ;
Upstream sequence
gtttgtttttccttttggtttttgagatggattcttgctctgtcacccaggctggagtgcagggacgtgatctcagctcactgcaacctccacctttcgc
Downstream sequence
gttccggtgattctcctgcctcagcctcccgagtaggtgggactataggcactcaccacaacgcccggctaatttttttgtatttttagtagaggcgggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate