VISDB Viral Integration Site DataBase

VIS ID

TVIS10007910

Fusion event

HBV-FMNL3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

3057

Orient

-

Integrated sequence

AACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGG| |CTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAA

Chromosome

chr12

Cytoband

q13.12

Reference genome

Start

End

50094350/49700567 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-125b-5p ; hsa-mir-182-5p ; hsa-mir-335-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-5579-3p ; hsa-mir-2467-3p ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4468 ; hsa-mir-4257 ; hsa-mir-196b-5p ; hsa-mir-196a-5p ; hsa-mir-4453 ; hsa-mir-4538 ; hsa-mir-2278 ; hsa-mir-8085 ; hsa-mir-6090 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-564 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6746-5p ; hsa-mir-3622a-5p ; hsa-mir-6873-5p ; hsa-mir-3915 ; hsa-mir-7160-5p ; hsa-mir-3928-3p ; hsa-mir-1537-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-6845-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-6838-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-211-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-3649 ; hsa-mir-4733-3p ; hsa-mir-6079 ; hsa-mir-671-5p ; hsa-mir-6753-5p ; hsa-mir-6828-5p ; hsa-mir-7113-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/928530; hsa-let-7i/Downstream/533575;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/76884, chr12-CpG: 116/Downstream/6092

Upstream sequence

actttgggaggccgaggcaggtgggtcgcgtgaggtcaggagtttgagatcagcctggccaacgtggcaaaaacccatctctaatgaaactacaaaaatt

Downstream sequence

agccaggcatggtggcatgcacctgtaatcccagttactcaggaggttgaggcagaagaattgcttgaacccaggaagcagaggttacagtgagccgaga