VISDB Viral Integration Site DataBase

VIS ID

TVIS10007917

Fusion event

HBV-YY1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1827

Orient

-

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT

Chromosome

chr14

Cytoband

q32.2

Reference genome

Start

End

100734676/100268339 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-31-5p ; hsa-mir-93-5p ; hsa-mir-769-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-221-3p ; hsa-mir-7-5p ; hsa-mir-205-5p ; hsa-mir-34b-3p ; hsa-mir-34c-5p ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-4722-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-548aw ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-4758-5p ; hsa-mir-1238-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1909-5p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-4496 ; hsa-mir-651-3p ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-5007-3p ; hsa-mir-27b-5p ; hsa-mir-1279 ; hsa-mir-5588-3p ; hsa-mir-8066 ; hsa-mir-183-5p ; hsa-mir-892b ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-491-3p ; hsa-mir-568 ; hsa-mir-4795-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-4729 ; hsa-mir-3941 ; hsa-mir-6504-3p ; hsa-mir-586 ; hsa-mir-3976 ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-543 ; hsa-mir-571 ; hsa-mir-219a-1-3p ; hsa-let-7c-3p ; hsa-mir-3177-5p ; hsa-mir-6793-3p ; hsa-mir-3613-3p ; hsa-mir-338-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-374b-3p ; hsa-mir-5682 ; hsa-mir-585-5p ; hsa-mir-6507-5p ; hsa-mir-511-5p ; hsa-mir-3613-5p ; hsa-mir-6830-3p ; hsa-mir-3133 ; hsa-mir-5590-3p ; hsa-mir-340-5p ; hsa-mir-142-5p ; hsa-mir-186-5p ; hsa-mir-219a-2-3p ; hsa-mir-4522 ; hsa-mir-6870-3p ; hsa-mir-138-1-3p ; hsa-mir-3679-3p ; hsa-mir-6840-5p ; hsa-mir-2115-5p ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-548o-3p ; hsa-mir-5582-3p ; hsa-mir-1323 ; hsa-mir-1273h-5p ; hsa-mir-1299 ; hsa-mir-149-3p ; hsa-mir-204-3p ; hsa-mir-2467-5p ; hsa-mir-30b-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-378a-3p ; hsa-mir-378b ; hsa-mir-378c ; hsa-mir-378d ; hsa-mir-378e ; hsa-mir-378f ; hsa-mir-378h ; hsa-mir-378i ; hsa-mir-422a ; hsa-mir-4314 ; hsa-mir-4638-3p ; hsa-mir-4646-5p ; hsa-mir-4728-5p ; hsa-mir-4778-5p ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-5706 ; hsa-mir-619-5p ; hsa-mir-630 ; hsa-mir-6506-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-455-3p ; hsa-mir-5689 ; hsa-mir-5696 ; hsa-mir-6516-5p ; hsa-mir-1281 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-139-3p ; hsa-mir-2276-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3913-5p ; hsa-mir-4294 ; hsa-mir-431-5p ; hsa-mir-4485-5p ; hsa-mir-450a-1-3p ; hsa-mir-6513-5p ; hsa-mir-6731-5p ; hsa-mir-6778-3p ; hsa-mir-6788-5p ; hsa-mir-6878-5p ; hsa-mir-6890-3p ; hsa-mir-8085 ; hsa-mir-887-5p ; hsa-mir-924

Nearest miRNA

hsa-mir-1260a/Upstream/158586; hsa-mir-1185-1/Downstream/9018;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/27609, chr14-CpG: 72/Downstream/16996

Nearest cancer related gene

YY1(OG, No orient, 0)

Upstream sequence

TTCAGGCTCATGCTGCACTCAGCCTAGACTGCCTAGTAAATCAGTTACATACGCACATGGGCAAAATATAAGCCATAATGACTTTAATTGGAAAGTCTGA

Downstream sequence

CATTGGGAAGGTGGACAGTCTATGGATGACTTTTTTTCCCGAAATGTCTGTTCAGTAAACATTTTGAAAAGTGGTCAGTGAGTGGTCCAGTGAGTTCTGT