VISDB Viral Integration Site DataBase

VIS ID

TVIS10007926

Fusion event

HBV-APOH integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2692

Orient

+

Integrated sequence

TGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGT| |ATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAA

Chromosome

chr17

Cytoband

q24.2

Reference genome

Start

End

64224495/66228377 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6738-3p ; hsa-mir-640 ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-103a-2-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6836-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-378a-5p ; hsa-mir-3653-5p

Nearest miRNA

hsa-mir-10226/Upstream/1406275; hsa-mir-1250/Downstream/558695;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/35909, chr17-CpG: 183/Downstream/73552

Upstream sequence

GTGTACTGTTACCAATTATAAgcataccaagttgcatgccaaatacctcatatacactatctcatctaatcccctcaacaaccatttgaaggaggtatta

Downstream sequence

taattatccccattttacaggtcagtatgctgaggcttaaattggctacgtatcttacAGAGGAGCTTTACACATGGCAATATTAAAGAATCAGTATCAA