VISDB Viral Integration Site DataBase

VIS ID

TVIS10007942

Fusion event

HBV-FTCD integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2388

Orient

-

Integrated sequence

TCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCG| |CCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACT

Chromosome

chr21

Cytoband

q22.3

Reference genome

Start

End

47563371/46143457 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-193b-5p ; hsa-mir-7155-5p ; hsa-mir-1976 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-668-3p ; hsa-mir-483-3p

Nearest miRNA

hsa-let-7c/Upstream/665131;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/10742, chr21-CpG: 83/Downstream/1914

Upstream sequence

ccctaccccccctccccatctccctcttgtgggcggcaagccagccaggtgcccaggcaagagaccgagggcacgagctgttttagtacaataaaatata

Downstream sequence

taaaataacaagagttgtactagatatagatcatagatatgattatatataattattaatcattagtttgtagcaattactctttaacattataataatc