VISDB Viral Integration Site DataBase

VIS ID

TVIS10007943

Fusion event

HBV-TXNRD2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2742

Orient

+

Integrated sequence

CTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAG| |ACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAT

Chromosome

chr22

Cytoband

q11.21

Reference genome

Start

End

19900035/19912512 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-17-3p ; hsa-mir-671-5p ; hsa-mir-106b-5p ; hsa-mir-6762-3p ; hsa-mir-5191 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6765-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-7851-3p

Nearest miRNA

hsa-mir-3198-1/Upstream/1931551; hsa-let-7a-3/Downstream/51241;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/4607, chr22-CpG: 37/Downstream/29061

Upstream sequence

CCTGCTGGATCCCCTGTGAGCCCAAAGAGCCGTCAGCAGCTGCCCGTGAGGTGCAGAGCAGGGCCGGGCCAGGCCAGGGCCCCTGTGCAGTGCTCCCTGG

Downstream sequence

TGCGGATGCACGTGCAGCTCTGCCTGGGGCCTCAGAGAAACCCAATGACCGCTGGGCTGCTGGAAGCTGGCTGTGGCCTTCTTTAAGCAGAACCACCATG