Fusion event
HBV-chr5 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
AGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCC| |AGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGA
End
161071034/161644028 (Hg38)
Nearest miRNA
hsa-mir-10397/Upstream/1158578; hsa-mir-103a-1/Downstream/6521817;
Upstream sequence
AAAAACCTGTTTAGATTTATTTTAATCACCAACAGTCATTCTCAGTGATAACTCTTCATCGCAAATTTGAGCACATAAAATTCCAGAGGAGTTAACATAA
Downstream sequence
tcaaaaataaagccaaccagggtaaaccagtgactaactatagagagatacacatattcaatgacactttggaactcctagttccattcatttttcatgt
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.