Basic Information
VIS ID
TVIS10007959
Fusion event
HBV-chr5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1318
Orient
+
Integrated sequence
TCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGC| |AAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACG
Host Sequence
Chromosome
chr5
Cytoband
p12
Reference genome
GRCh37/hg19
Start
45843536/45843434 (Hg38)
End
45843536/45843434 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/7285873; hsa-mir-103a-1/Downstream/8108070;
Nearest TSS
ENST00000502646/Upstream/146936; ENST00000510987/Downstream/46782;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/147026, chr5-CpG: 79/Downstream/4597339
Nearby gene
HCN1(-147316) ;
Upstream sequence
TCTGCCTCAGTCACAGTTGAAAGTCTTTAAAGTCTTTtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgtTTCgtagaga
Downstream sequence
TTGTGTAATTTAAGAAAAAGCACTTTCCCTGTATTCTTGCCTATGCATTTTCCTTCAGAAAGTTGAGATTTCAAGAGAGAAGAAATTGTAGATTTAATTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate